Dictionary.com
Thesaurus.com
Showing results for isolate. Search instead for to isolate.
Synonyms

isolate

American  
[ahy-suh-leyt, ahy-suh-lit, -leyt] / ˈaɪ səˌleɪt, ˈaɪ sə lɪt, -ˌleɪt /

verb (used with object)

  • isolates,
    present (3rd person singular)
  • isolated,
    past participle,  past
  • isolating
    present participle
  1. to set or place apart; detach or separate so as to be alone.

  2. Medicine/Medical. to keep (an infected person) from contact with noninfected persons; quarantine.

  3. Chemistry, Bacteriology. to obtain (a substance or microorganism) in an uncombined or pure state.

  4. Electricity. to insulate.

  5. Television. to single out (a person, action, etc.) for a camera closeup.


noun

  1. a person, thing, or group that is set apart or isolated, as for purposes of study.

  2. Psychology. a person, often shy or lacking in social skills, who avoids the company of others and has no friends within a group.

  3. Biology. an inbreeding population that is isolated from similar populations by physiological, behavioral, or geographic barriers.

  4. Also called language isolateLinguistics. a language with no demonstrable genetic relationship, as Basque.

  5. something that has been isolated, as a by-product in a manufacturing process.

    an isolate of soy flour.

adjective

  1. isolated; alone.

isolate British  

verb

  1. to place apart; cause to be alone

  2. med to quarantine (a person or animal) having or suspected of having a contagious disease

  3. to obtain (a compound) in an uncombined form

  4. to obtain pure cultures of (bacteria, esp those causing a particular disease)

  5. electronics to prevent interaction between (circuits, components, etc); insulate

"Collins English Dictionary — Complete & Unabridged" 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

noun

  1. an isolated person or group

"Collins English Dictionary — Complete & Unabridged" 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

Other Word Forms

Derived Forms

Inflected Forms

Participles

Conjugated Forms

Present

Past

Future

Etymology

Origin of isolate

First recorded in 1800–10; back formation from isolated

Explanation

When you remove or set apart one thing from others, you isolate it. You could isolate yourself from people by living in a remote hut or, if you're a biologist, you could isolate a chromosome. The verb isolate comes from the adjective isolated, which comes from the Latin insulatas, meaning “made into an island.” You may have heard the John Donne quote, “No man is an island.” Donne was claiming that no matter how much you might try to isolate yourself from the rest of humanity, in the end people are all connected to one another. Humanity’s need for connectedness may, in fact, be illustrated by the fact that jailers frequently isolate criminals as punishment.

Keep Reading on Vocabulary.com

Vocabulary lists containing isolate

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

See Examples For:

Spanish Prime Minister Pedro Sánchez criticized calls to isolate Spain, arguing the country’s border controls remain intact and warning against measures that could undermine European unity.

From Salon Aug. 1, 2026

Then there’s the fact that Nicaraguan migrants in the United States are a smaller and less powerful force than Cuban Americans, many of whom have lobbied Washington for decades to isolate and overthrow Havana’s leaders.

From Los Angeles Times Jul. 26, 2026

Traditional laboratory methods can isolate and identify peptides, but the process can produce enormous amounts of data.

From Science Daily Jul. 24, 2026

The incubation period of Ebola ranges from two to 21 days and the humanitarian worker will be required to isolate throughout.

From BBC Jul. 22, 2026

Then imagine the skill required to isolate this particle, to take it apart and analyze its components and determine their highly complex functioning.

From "Silent Spring" by Rachel Carson

While Mr. Graham-Dixon isolates the technical from the theological, Mr. Weber integrated the “optical and iconographic” aspects of Vermeer’s life and work.

From The Wall Street Journal Jun. 26, 2026

By operating as a separate entity, GenCo isolates the cost of new growth to data centers, according to NiSource.

From Barron's Apr. 16, 2026

To identify these enzymes, the research team used a technique that isolates proteins physically attached to chromatin, the natural packaging of DNA in human cells.

From Science Daily Mar. 9, 2026

"We want to build a care system that supports them, not isolates them."

From BBC Aug. 18, 2025

A waist-high barrier isolates it from the rest of the space.

From "The Belles" by Dhonielle Clayton

Quarks and gluons cannot remain isolated, so after the collision they quickly combine with other particles.

From Science Daily Aug. 16, 2026

And if people prefer a congenial bot over messy human relationships, they can lose social skills, become isolated, or even spiral.

From The Wall Street Journal Aug. 16, 2026

Ricky Bobby lives in a McMansion in some isolated North Carolina community.

From Salon Aug. 16, 2026

The move came partly because of their isolated location in the north of the territory among many Palestinian cities and villages.

From Barron's Aug. 13, 2026

Many of the isolated, heavily defended camps were on hilltops in remote locations near Vietnam’s western border with Cambodia and Laos where Special Forces could keep track of enemy movement.

From "Boots on the Ground: America's War in Vietnam" by Elizabeth Partridge

The setup made it possible to recreate extreme conditions that ordinary solid materials cannot reach while isolating the effects of particle collisions.

From Science Daily Jul. 31, 2026

"Decisions of state are not made by one person alone, and they cannot be judged honestly by isolating one moment from the whole crisis," she said.

From Barron's Jul. 29, 2026

Unlike deaths with associated rituals, road maps, and standards, those that are disenfranchised are complex, underacknowledged, and often isolating.

From Slate Jul. 19, 2026

A monthslong internet blackout has severely disrupted online commerce, further isolating the youth demographic.

From The Wall Street Journal Jun. 29, 2026

Increasingly, the nation’s richest are spending their money on personal services or exclusive experiences and isolating themselves from the masses in ways that go beyond building gated walls.

From "Class Matters" by The New York Times

Vocabulary.com logo
by dictionary.com

Dictionary.com's Learning Companion

Go beyond just looking up words.
Remember them forever with VocabTrainer.

Start training